CryoLife Inc.:
Probably the U.S. leader in research and cryopreservation of heart
valves for transplant. Also preserves vascular tissue for heart
bypass and vascular resonstruction, and connective tissue (tendons).
Is also doing research in surgical glues.
http://www.cryolife.com/
National Seed Storage Laboratory (NSSL):
The section on "Preservation" discusses cryogenic storage.
http://www.ars-grin.gov/ars/NoPlains/FtCollins/nsslmain.html
Cryobiology Aachen:
An elaborate set of pages with a great deal of general and technical
information from Ingo Heschel at the Helmholtz-Institute for
Biomedical Engineering at the Aachen University of Technology.
http://www-users.rwth-aachen.de/Ingo.Heschel/index.html
Freeze-Drying Homepage:
From Volker Rindler at the Helmholtz-Institute for Biomedical
Engineering at the Aachen University of Technology. Emphasis on
freeze-drying red blood cells.
http://www-users.rwth-aachen.de/Volker.Rindler/Cryo.html
Asymptote Cool Guide to Cryopreservation:
Manual of the general principles of cryobiology, especially
regarding the preservation of sperm and embryos. Detailed but
accessible to the educated layman.
http://www.asymptote.co.uk/cryo/manual.shtml
BioLife Technologies, Inc.:
Researches preservative solutions used in cell and tissue cultures
and in human organ transplants, especially Hypothermosol. Subsidiary
of Cryomedical Sciences, Inc.
http://www.cryomedical.com/R&D/BioLife.htm
Cryomedical Cell Suicide Following Cryosurgery:
Research summary of discovery that standard cryosurgical methods
cause gene-activated apoptosis near the surgical site. This might be
a general clue to some kinds of freezing damage. By John G. Baust,
Ph.D. and Robert Van Buskirk, Ph.D
http://www.cryomedical.com/R&D/apoptosi.htm
21st Century Medicine:
A research and development company in the fields of cryopreservation
and ice control technologies for cryobiology and industrial uses. In
Rancho Cucamonga, California.
http://www.21CM.com/
Lyophilization Services of New England, Inc.:
Contract manufacturer providing lyophilization (freeze-drying) of
products, both vial and bulk. In Manchester, New Hampshire.
http://www.lyophilization.com/
Cryosite:
A company which provides secure off-site, ultra-low temperature and
cryogenic storage for biological specimens. In Sydney, Australia.
http://www.cryosite.com
Biolyph's Lyophilization Services:
Lyophilization (freeze-drying) and contract manufacturing of
pharmaceutical and diagnostic products using LyoSpheres. In Hopkins,
Minnesota.
http://www.freeze-drying-lyophilization.com/
Cryopreservation Research:
Research on trehalose and cryopreservation at University of
Wisconsin, Molecular Thermodynamics and Statistical Mechanics Group.
Click on "Research." Includes a link to their nanolithography
program.
http://www.engr.wisc.edu/groups/mtsm/
Frozen Fruit Fly Embryos Hatched:
An article from "Technical Highlights" in the Oak Ridge National
Laboratory Review (Vol. 26, No. 1). Reports the research of Peter
Mazur and others from 1992.
http://www.ornl.gov/ORNLReview/rev26-1/net1026.html
Phase Technologies:
An organization dedicated to the lyophilization (freeze-drying)
process that is used in the manufacture of pharmaceutical,
biotechnology, and diagnostic products. Also provides lyophilization
services. In Bala Cynwyd, Pennsylvania.
http://www.phase-technologies.com/
Freezing fruit flies for future research:
An article updating the Peter Mazur research at Oak Ridge National
Laboratory. From "Technical Highlights" in the ORNL Review from
1993. You have to page down about halfway for the article on Mazur.
http://www.ornl.gov/ORNLReview/rev26-34/text/tecmain.html
Cryopreservation Application Guide:
A manual for the cryopreservation of cells, as a downloadable PDF
file (requires Adobe Acrobat plug-in). From Nalgene Nunc.
http://nalgenelab.nalgenunc.com/select/app/cryo/
BioMonde: Research and Development:
Bulgarian cryobiology researchers claim to have freeze-dried,
stored, and transplanted "most of the vital organs." No details;
claims appear to be of dubious credibility. Supposedly part of the
Bulgarian Institute of Cryobiology and Lyophilisation.
http://bio-monde.com/r&d.htm
LifeNet:
LifeNet is the largest, full-service, non-profit allograft Tissue
Banking System in the United States. LifeNet is also a non-profit,
federally-designated, Organ Procurement Organization providing
donation systems for heart, liver, kidney, pancreas,lung, and other
organs for transplant.
http://www.lifenet.org/
Cryo-By-Design:
Cryo-By-Design is an innovative company that offers quality
instrumentation, manufactured by an award winning company, since
1992 for cryo-preservation and freeze-substitution.
http://www.cryotrain.com
Cryobiology: Low temperature studies of biological systems:
A readable summary of the field of cryobiology by a college biology
student, but with some confused opinions about the intent of the
field.
http://199.8.232.90/bio/Biol410/BSSpapers99/krista/Krista.htm
International Bioresearch Solutions:
IBS is a non-profit national organization that works with organ
procurement organizations to place organs that are not suitable for
transplant with medical researchers.
http://www.researchtissue.org
Cryolab - Roskilde University:
Cryobiology laboratory at Roskilde University, Denmark.
Concentration on cold adaptation in animals, with ongoing research
in antifreeze proteins, microtubules, cryopreservation.
http://virgil.ruc.dk/~cryolab
Ken Storey's Lab:
The "frozen frog" expert at Carleton University, Ottawa, Ontario,
Canada.
http://www.carleton.ca/~kbstorey/
Society for Cryobiology:
The primary scientific society in this field, founded in 1964 to
promote research into the effects of low temperatures on all types
of organisms and their constituent cells, tissues and organs.
http://www.societyforcryobiology.org/
Cryobiology:
International journal of low temperature biology and medicine.
Published by the Society for Cryobiology.
http://www.sciencedirect.com/science/journal/00112240
